Implementing Genome-Driven Oncology

In this review article physicians from Memorial Sloan-Kettering Cancer Center describe the related challenges associated with implementing ‘Genome-Driven’ oncology.

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Emerging patterns of somatic mutations in cancer

The article highlights the developing statistical approaches that are used to identify significantly mutated genes, and discuss the emerging biological and clinical insights from such analyses, as well as the future challenges of translating these genomic data into clinical impacts.

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Why Gene Tests for Cancer Don’t Offer More Answers

Researchers refer to the abnormal changes that are integral to a tumor’s growth and survival as driver mutations; the others are known as passenger mutations because they appear to be unimportant and seemingly are just along for the ride.

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